General / Multi-Symptom

Diagnostic Value of ALCAT Test in Intolerance to Food Additives Compared with Double-Blind Placebo-Controlled (DBPC) Oral Challenges
Efficiency: 96% Conclusively, the ALCAT Test seems to provide a high efficiency in detecting food additive intolerance with few-false positives and it deserves further studies on larger material. Lene Hoj, MD. Presented at 52nd annual meeting of the American Academy of Allergy, Asthma & Immunology; March 15-20, 1996, New Orleans, Published – Journal of Allergy and Clinical Immunology, Vol. 97, No. 1, Part 3, January 1996.

Rational management of food intolerance in elite soccer club
A team of investigators led by Fabrizio Angelini studied eight elite (European football) athletes who were selected based on symptoms suspected of being food related. These athletes were placed on an ALCAT based-elimination diet, followed for eight months then retested again. There was significant improvement in the athletes’ condition and reduction in inflammatory response as seem through improvement in body composition.Published in Journal of the International Society of Sports Nutrition 2011, Volume 8 (Supplement 1). Angelini, F., Marzatico, F., Stesina, G., Stefanini, L., Bonuccelli, A., Buonocore, D.

High Correlation of the ALCAT Test Results with Double-Blind Challenge (DBC) in Food Sensitivity
Investigators PJ Fell PJ, J Brostoff, and MJ Pasula demonstrated in a study of 19 patients an overall correlation between ALCAT and DBC at 83.4%, suggesting that the ALCAT Test was quite reliable in identifying unsafe foods in these sensitive subjects. Presented at 45th Annual Congress of the American College of Allergy and Immunology, Los Angeles, CA: November 12-16, 1988 Peter I. Fell, MD, Director; Oxford Allergy Centre, London Jonathon Brostoff, MA DM USc FRCP FRCPath, Dept. of Immunology, University College & Middlesex School of Medicine, London Mark I. Pasula, Ph.D., Research Director; AMTL Corp., Miami, FL

A Comparison of the ALCAT Test for Food Reactions amongst 2 Population Sub-Groups
Investigators Douglas H. Sandberg and MJ Pasula concluded the ALCAT Test demonstrated a distinct difference in reactivity between a healthy group and a group of patients with food sensitivities. Presented at 45th Annual Congress of the American College of Allergy and Immunology, Los Angeles, CA: November 12-16, 1988 (published in the Annals of Allergy Congress Preceding) Douglas H. Sandberg, MD, Professor, University of Miami Medical School, Miami, FL, Mark J. Pasula, Ph.D., Research Director AMTL Corp., Miami, FL.

Multiple Pathogenic Mechanisms in Food Sensitivity Reactions In-Vitro
Investigators MJ Pasula and S Puccio found the activation of multiple immunological mechanisms were observed when whole blood aliquots were exposed to and incubated with food extracts. Presented at 4th International Symposium on Immunological and Clinical Problems of Food Allergy. Milan, Italy: November 5-9, 1989. Mark J. Pasula, Ph.D., Research Director, AMTL Corp., Miami, FL, Samy Puccio, Research Assistant, AMTL Carp., Miami, FL.

Influence of Food Antigens on Volumes of Circulating White Blood Cells and Platelets Aggregation
Fell and Brostoff reported over 70% correlation between Double Blind Oral Food Challenges and ALCAT Test scores based upon WBC changes alone (74 positive and 68 negative challenges.)Mark J. Pasula, Ph.D., Research Director, AMTL Corp., Miami, FL, Presented at the 4th International Symposium on Immunological and clinical Problems of Food Allergy. Milan, Italy: November 5-9, 1989. Published in the Proceedings.

ALCAT- “A New Test for Food Induced Problems in Medicine?” 
Conclusions: The ALCAT test works in a clinical situation predicting a dietary programme which benefits a wide range of patients suffering from a variety of clinical conditions. ALCAT Positive and negative predictions correlate with subsequent food challenges in a statistically significant number of cases. Presented at the annual meeting of the American Academy of Otolaryngic Allergy, Oct 1, 1988; Washington, D.C. Drs. P.J. Fell, J. Brostoff, H. O’Donnell

Inhibitory Effect of Sodium Cromoglycate on Granulocyte Response to Food Antigens In Vitro
Investigators PJ Fell, Sandberg, and Pasula confirmed in a pilot study that cellular reactions observed through the ALCAT Test can be attributable to an immunological mechanisms based on the interactions with sodium cromoglycate. Presented at 47th annual meeting of the American College of Allergy & Immunology, November 10-14, 1990, San Francisco, CA. D.H. Sandberg, MD, M.J. Pasula, PhD, P.J. Fell, Miami, FL and UK

Pilot Study Into The Effect of Naturally Occurring Pharmacoactive Agents on the ALCAT Test
Investigator PJ Fell used the ALCAT test to successfully determine cellular reactions to Pharmacoative agents found in foods that trigger migraine headaches. Presented at Annual Meeting of the American Otolaryngic Allergy Association, September 27, 1991; Kansas City, MO. P.J. Fell, MD

ALCAT Test Results In The Treatment of Respiratory and Gastrointestinal Symptoms, Arthritis, Skin and Central Nervous System
Investigator Danuta Mylek studied 72 patients who followed an ALCAT based elimination diet; they had significant improvement in their symptoms that included arthritis, bronchitis and gastro issues. Specifically, they found improvement in 83% of arthritis patients, 75% of Urticaria, bronchitis, and gastroenteritis patients, 70% of migraine patients, 60% of chronic fatigue syndrome patients, 50% of asthma patients, 49% of AD patients, 47% of rhinitis patients and 32% of hyperactivity patients. Patients were also skin tested for IgE allergy to inhalants and foods that were more pronounced in skin and nasal symptoms. Published in Advances in Medical Sciences; Formerly Roczniki Akademii Medycznej w Białymstoku Volume 40, Number 3, 1995.

The ALCAT Test – A Guide and Barometer in the Therapy of Environmental and Food Sensitivities
Investigator Barbara A. Solomon MD studied 172 patients successfully using an ALCAT Test-based diet to alleviate the following range of symptoms: classic migraine (85%), common migraine (62%), sinus headaches (58%), gastoesphageal reflux (GERD) (75%), IBS (71%), inflammatory arthritis (65%), recurrent Sinusitis (59%), tension fatigue, syndrome (60%), obesity (50%), eczema (55%), asthma (30%), depression and/or anxiety (31%), recurrent vaginitis (20%), recurrent urinary tract infection (46%), degenerative arthritis (44%) and allergic rhinitis (42%). Published in Environmental Medicine, Volume 9, Number 1 & 2, 1992. Barbara Solomon MD, MA

Inflammatory Symptoms, Immune System and Food Intolerance. One Cause – Many Symptoms
Dr. rer.nat. Silvia Slazenger.